Fourth Building, Section B J19
[Biofunctional Chemistry ; Biotechnology]
Thursday, March 16, AM
Chair: HAYASHI, Gosuke
(09:00-10:00)
* 8:50-9:00: interval for laptop PC connection.(1C4-01, 1C4-02, 1C4-03, 1C4-04, 1C4-05)
1C4-01
Control of Electronic Property of Single DNA Molecule by Intercalation (Sch. Sci., Tokyo Tech.) º HARASHIMA, Takanori; NISHINO, Tomoaki
1C4-02
Construction of stacked thiazole oranges and control of their emission properties using DNA structure (Grad. Sch. Eng., Univ. of Hyogo) º HONDA, Yurika; TAKADA, Tadao; ISHINO, Shunya; NAKAMURA, Mitsunobu; YAMANA, Kazushige
1C4-03
A study on energy migration between identical fluorophores by using DNA scaffold (Nagoya Univ.) º KAWAI, Hayato; MARUYAMA, Ryoko; KASHIDA, Hiromu; ARAKI, Yasuyuki; WADA, Takehiko; ASANUMA, Hiroyuki
1C4-04
Difference of electron-transfer modes between electrode-bound, single- and double-stranded DNAs modified with a redox-active moiety (Fac. Pharm. Sci., Univ. of Toyama) º AOKI, Shun; CHIBA, Junya; INOUYE, Masahiko
1C4-05*
Development of Distance and Orientation Controlled FRET System Using Emissive dG-dC Analogue Pair (Dep. Chem., Sch. Sci., Kyoto Univ.) YAMAMOTO, Seigi; º HAN, Jihun; PARK, Soyoung; SUGIYAMA, Hiroshi
Chair: ASANUMA, Hiroyuki
(10:10-11:10)
* 10:00-10:10: interval for laptop PC connection.(1C4-08, 1C4-09, 1C4-10, 1C4-12)
1C4-08
Sequence-Specific Detection of Methylated DNA with Chemical Probes (Fac. Eng., The Univ. of Tokyo) º TAKEUCHI, Fumika; OKAMOTO, Akimitsu
1C4-09
Development of a high-resolution method to detect 5-hydroxymethycytosine by peroxotungstate and DNA sequencing and its application to genomic DNA (Fac. Eng., The Univ. of Tokyo) º KOHYAMA, Kenta; OKAMOTO, Akimitsu; HAYASHI, Gosuke
1C4-10*
Recognition of 5-methylcytosine and 5-methyluridine in RNA by Osmium Oxidation (The Univ. of Tokyo) º DEBNATH, Turja Kanti; OKAMOTO, Akimitsu
1C4-12*
Development of new chemical modification method for analysis of unique G-quadruplex structures (Fac. Med., Univ. of Miyazaki) º ISHIZUKA, Takumi; BAO, Hong-liang; XU, Yan
Chair: NAGATOISHI, Satoru
(11:20-12:20)
* 11:10-11:20: interval for laptop PC connection.(1C4-15, 1C4-16, 1C4-17, 1C4-18, 1C4-20)
1C4-15
Highly sensitive detection of nucleic acids in a single cell with L-DNA tag (RCAST, The Univ. of Tokyo; Grad. Sch. Eng., The Univ. of Tokyo) º ICHIU, Anri; HAYASHI, Gosuke; OKAMOTO, Akimitsu
1C4-16
Imaging analysis of RISC localization mechanism by using siRNA involving dye pair. (Grad. Sch. Eng., Nagoya Univ.) º SATAKE, Mayu; KAMIMOTO, Hiroshi; ITO, Anna; KAMIYA, Yukiko; ASANUMA, Hiroyuki
1C4-17
Development of bioorthogonal SERS probes and their application to nucleic acid detection. (KIT) º OTA, Ryo; TAKAGI, Noriyuki; NAGAI, Yuki; SUGIHARA, Yuta; KOBORI, Akio
1C4-18*
Visualization of human telomeres with pyrrole-imidazole polyamides targeting human telomeric repeats (Dep. Chem., Sch. Sci., Kyoto Univ.; Sch. Life Sci., SOKENDAI) º KAWAMOTO, Yusuke; CHANDRAN, Anandhakumar; BANDO, Toshikazu; MAESHIMA, Kazuhiro; SUGIYAMA, Hiroshi
1C4-20
Selective targeting of mitochondrial DNA by a synthetic DNA-Binding molecule (Dep. Chem., Sch. Sci., Kyoto Univ.; WPI-iCeMS, Kyoto Univ.) º HIDAKA, Takuya; NAMASIVAYAM, Ganesh Pandian; BANDO, Toshikazu; SUGIYAMA, Hiroshi
Thursday, March 16, PM
Chair: KUWAHARA, Masayasu
(13:40-14:40)
* 13:30-13:40: interval for laptop PC connection.(1C4-29, 1C4-31, 1C4-33)
1C4-29*
Live-Cell Imaging of Bioorganic Molecules with a Small Molecule and a Short RNA (ICR, Kyoto Univ.) º YATSUZUKA, Kenji; SATO, Shinichi; KATSUDA, Yousuke; PE, Beverly Kathleen; UESUGI, Motonari
1C4-31*
Exploration the RNA G-quadruplex using a small molecule (WPI-iCeMS, Kyoto Univ.) º KATSUDA, Yousuke; SATO, Shinichi; YATSUZUKA, Kenji; UESUGI, Motonari
1C4-33*
ATP sensors selected from a fluorophore library (IAE, Kyoto Univ.) º NAKANO, Shun; TAMURA, Tomoki; CHANG, Young-tae; MORII, Takashi
Chair: MORII, Takashi
(14:50-15:50)
* 14:40-14:50: interval for laptop PC connection.(1C4-36, 1C4-38, 1C4-39, 1C4-41)
1C4-36*
Detection of gene mutations using signal amplification by ternary initiation complexes (SATIC) (Grad. Sch. Sci. Tech., Gunma Univ.) º FUJITA, Hiroto; KATOKA, Yuka; KUWAHARA, Masayasu
1C4-38
Detection of biomolecules using signal amplification by ternary initiation complexes (SATIC) (Grad. Sch. Sci. Tech., Gunma Univ.) º NAGANO, Remi; FUJITA, Hiroto; KATAOKA, Yuka; KUWAHARA, Masayasu
1C4-39*
Development of signal amplification circuit composed of acyclic artificial nucleic acids for detection of RNA (Grad. Sch. Eng., Nagoya Univ.) º MURAYAMA, Keiji; NAGAO, Ryuya; ASANUMA, Hiroyuki
1C4-41
Research for prebiotic synthetic pathway of ribonucleoside (Grad. Sch. Eng., The Univ. of Tokyo; RCAST, The Univ. of Tokyo) º USAMI, Kaho; OKAMOTO, Akimitsu
Chair: ENDOH, Tamaki
(16:00-17:00)
* 15:50-16:00: interval for laptop PC connection.(1C4-43, 1C4-44, 1C4-45, 1C4-47, 1C4-48)
1C4-43
Development of efficient alkylating probes targeting double-stranded DNA containing an abasic-site (IMRAM, Tohoku Univ.) º TANNO, Kousuke; YAMADA, Ken; SASAKI, Yoshihiro; SATO, Norihiro; ONIZUKA, Kazumitsu; NAGATSUGI, Humi
1C4-44
Selective G-quadruplex alkylation by vinyl triazine derivatives (IMRAM, Tohoku Univ.) º HAZEMI, Madoka Eurika; USAMI, Akira; KOBAYASHI, Tomohito; SATO, Norihiro; ONIZUKA, Kazumitsu; NAGATSUGI, Fumi
1C4-45*
Mechanistic study of pseudorotaxane formation via the slipping process targeting on nucleic acids (IMRAM, Tohoku Univ.) º ONIZUKA, Kazumitsu; CHIKUNI, Tomoko; MIYASHITA, Takuya; NAGATSUGI, Fumi
1C4-47
Investigation of stabilization and biofunction of Z-RNA and Z-DNA/Z-RNA hybrid helix stabilized by 2’-O-methyl-8-methylguanosine a Z-form stabilizer (Fac. Med., Univ. of Miyazaki) º BALASUBRAMANIYAM, Thananjeyan; ISHIZUKA, Takumi; XU, Yan
1C4-48
Photo-driven DNA strands displacement mediated by azobenzene-tethered oligonucleotide (Grad. Sch. Eng., Nagoya Univ.) º CHENG, Bohao; KASHIDA, Hiromu; SHIMADA, Naohiko; MARUYAMA, Atsushi; ASANUMA, Hiroyuki
Chair: NAGATSUGI, Fumi
(17:10-18:10)
* 17:00-17:10: interval for laptop PC connection.(1C4-50, 1C4-51, 1C4-53, 1C4-55)
1C4-50
Investigation of the RNA adduct's contribution in cartinogenesis (Fac. Eng., The Univ. of Tokyo) º MORIYAMA, Yuya; OKAMOTO, Akimitsu
1C4-51*
Nucleic Acids Chemistry beyond the Watson-Crick Double Helix (28): A non-coding tRNA regulates functionally important G-quadruplex-hairpin conformational equilibria in RNA (FIBER, Konan Univ.) º RODE, Ambadas B.; ENDOH, Tamaki; SUGIMOTO, Naoki
1C4-53*
Nucleic Acids Chemistry beyond the Watson-Crick Double Helix (29) : Analysis of structural dynamics of RNA aptamer using high pressure (FIBER, Konan Univ.; FIBER, Konan Univ.) º TAKAHASHI, Shuntaro; ENDOH, Tamaki; RODE, Ambadas B.; SUGIMOTO, Naoki
1C4-55
An allosteric ribozyme which is responsible for a point mutation in a substrate RNA (Grad. Sch. Pharm. Sci., Tohoku Univ.) º YAMADA, Mituhiro; NUMAZAKI, Takumi; KONDO, Yoshinori; KATO, Yoshio; TANAKA, Yoshiyuki
Friday, March 17, AM
Chair: OHYA, Yuichi
(09:00-09:50)
* 8:50-9:00: interval for laptop PC connection.(2C4-01, 2C4-02, 2C4-03, 2C4-05)
2C4-01
Antitumor Activity by Sequence-Specific HAT Inhibitors (Dep. Chem., Sch. Sci., Kyoto Univ.) º YU, Zutao; TANIGUCHI, Junichi; WEI, Yulei; BANDO, Toshikazu; SUGIYAMA, Hiroshi
2C4-02
RBP-J Binding Inhibition Drives Human Neural Stem Cells Differentiation by Suppressing Hes-1 and Related Notch Signaling Pathway (Dep. Chem., Sch. Sci., Kyoto Univ.; WPI-iCeMS, Kyoto Univ.) º WEI, Yulei; NAMASIVAYAM, Ganesh Pandian; BANDO, Toshikazu; SUGIYAMA, Hiroshi
2C4-03*
Cardiomyocytes Induction By DNA Sequence-Specific Synthetic Molecules (Dep. Chem., Sch. Sci., Kyoto Univ.; WPI-iCeMS, Kyoto Univ.) º TANIGUCHI, Junichi; NAMASIVAYAM, Ganesh Pandian; BANDO, Toshikazu; SUGIYAMA, Hiroshi
2C4-05
In cell analysis of mRNA using molecular-beacon-modified nanoneedle (Grad. Sch. Fac. Eng., Tokyo Univ. of Agri. and Technol.) º NAITOH, Miuzki; YAMAGISHI, Ayana; MOGAMI, George; SUZUKI, Makoto; FUKAZAWA, Kyoko; ISHIHARA, Kazuhiko; NAKAMURA, Chikashi
Chair: SUGIMOTO, Naoki
(10:00-11:00)
* 9:50-10:00: interval for laptop PC connection.(2C4-07, 2C4-10, 2C4-12)
2C4-07 Young Scholar Lectures of CSJ
RNA Conformational Dynamics that Encodes New Dimensional Code in Central Dogma (FIBER, Konan Univ.) º ENDOH, Tamaki
2C4-10*
Functional oligonucleotide for regulation of cellular activities (1) Oligonucleotide-based growth factor mimetics -Regulation of cellular functions and its application- (Grad. Sch. Eng., The Univ. of Tokyo) º UEKI, Ryosuke; KANDA, Naoto; UCHIDA, Satoshi; CABRAL, Horacio; SANDO, Shinsuke
2C4-12
Functional oligonucleotide for regulation of cellular activities (2) Synthetic switch for input-dependent growth factor signaling (Grad. Sch. Eng., The Univ. of Tokyo) º ATSUTA, Saki; UEKI, Ryosuke; SANDO, Shinsuke
Chair: SUGIYAMA, Hiroshi
(11:10-12:00)
* 11:00-11:10: interval for laptop PC connection.(2C4-14, 2C4-16, 2C4-17)
2C4-14*
Application of DNA quadruplex hydrogels as biomaterial (Fac. Chem. Materials and Bioeng., Kansai Univ.) º TANAKA, Shizuma; FUKUSHIMA, Kazuki; WAKABAYASHI, Kenta; YUKAMI, Shinsuke; KUZUYA, Akinori; OHYA, Yuichi
2C4-16
Development of cell culture substrate utilizing DNA quadruplex hydrogels (Fac. Chem. Materials and Bioeng., Kansai Univ.) º YUKAMI, Shinsuke; TANAKA, Shizuma; FUKUSHIMA, Kazuki; WAKABAYASHI, Kenta; KUZUYA, Akinori; OHYA, Yuichi
2C4-17*
Topologically interlocked DNA nanostructures inside a DNA origami frame (IAE, Kyoto Univ.) º RAJENDRAN, Arivazhagan; PARK, Seo-jeong; NAKATA, Eiji; KWON, Youngjoo; MORII, Takashi
Friday, March 17, PM
Chair: TAKENAKA, Shigeori
(14:30-15:30)
* 14:20-14:30: interval for laptop PC connection.(2C4-34, 2C4-35, 2C4-36, 2C4-37, 2C4-38)
2C4-34
The development of the mismatch binding ligand which has RNA cleavage activity (ISIR, Osaka Univ.) º MIKI, Shota; YAMADA, Takeshi; NAKATANI, Kazuhiko
2C4-35
Nucleic Acids Chemistry beyond the Watson-Crick Double Helix (34): Construction of a ligand screening system targeting human telomeric DNA (FIRST, Konan Univ.) º IMAGAWA, Yoshiki; KOHATA, Kazuki; TERADA, Kosuke; MAEDA, Ryuichi; SUGIMOTO, Naoki; MIYOSHI, Daisuke
2C4-36
Simple screening method for ligands affecting CAG/CTG repeats stability (ISIR, Osaka Univ.) º BINTI MOHD ZAIFUDDIN, Nursakinah; LI, Jinxing; DOHNO, Chikara; NAKATANI, Kazuhiko
2C4-37
Sandwich-typed assays for microRNA quantification using pyrene probes (KIT) º WATARI, Yu; ARIYOSHI, Jumpei; SUGIHARA, Yuta; YAMAYOSHI, Asako; MURAKAMI, Akira; KOBORI, Akio
2C4-38*
Sensitive RNA detection by using stable dye pairs (Grad. Sch. Eng., Nagoya Univ.) º KASHIDA, Hiromu; MORIMOTO, Kazuhiro; ASANUMA, Hiroyuki
Chair: MIYOSHI, Daisuke
(15:40-16:30)
* 15:30-15:40: interval for laptop PC connection.(2C4-41, 2C4-43, 2C4-45)
2C4-41*
Cyclic naphthalene diimide derivatives connected with various linker chains containing benzene part and their interactions with tetraplex DNAs (Grad. Sch. Eng., KIT) MINEMATSU, Hiroki; WAKAHARA, Daiki; SAMESHIMA, Shino; SATO, Shinobu; FUJII, Satoshi; º TAKENAKA, Shigeori
2C4-43*
Cyclic naphthalene diimide derivatives connected with various alkyl linker chains and their interactions with tetraplex DNAs (Grad. Sch. Eng., KIT) SHINJO, Akina; TAKEUCHI, Ryusuke; º SATO, Shinobu; FUJII, Satoshi; TAKENAKA, Shigeori
2C4-45
Controlled release of Cas9-sgRNA complex using G-quadruplex formation (Grad. Sch. Fac. Eng., Tokyo Univ. of Agri. and Technol.; BRI, AIST) º TAKANO, Yuta; YAMAGISHI, Ayana; NISHIO, Maui; TSUKAKOSHI, Kaori; IKEBUKURO, Kazunori; KATO, Yoshio; NAKAMURA, Chikashi
Chair: MURAYAMA, Keiji
(16:40-17:40)
* 16:30-16:40: interval for laptop PC connection.(2C4-47, 2C4-48, 2C4-49, 2C4-51, 2C4-52)
2C4-47
Nucleic Acids Chemistry beyond the Watson-Crick Double Helix (30) : Investigation of stabilizing mechanism of G-quadruplexes by cyclic naphthalene diimide (FIBER, Konan Univ.; Grad. Sch. Eng., KIT; Grad. Sch. Sys. Info., Kobe Univ.; FIRST, Konan Univ.) º OHYAMA, Tatsuya; TATEISHI-KARIMATA, Hisae; TAKAHASHI, Shuntaro; SATO, Shinobu; TANAKA, Shigenori; TAKENAKA, Shigeori; SUGIMOTO, Naoki
2C4-48
Nucleic Acids Chemistry beyond the Watson-Crick Double Helix (31): The C-rich sequence in non-template strand determines the structure of G-rich template during transcription (FIBER, Konan Univ.) º TENG, Ye; TATEISHI, Hisae; SUGIMOTO, Naoki
2C4-49*
Nucleic Acids Chemistry beyond the Watson-Crick Double Helix (32): Relationship of malignant alteration in cancer cells and the transcript mutations via DNA G-quadruplex formation (FIBER, Konan Univ.) º TATEISHI-KARIMATA, Hisae; KAWAUCHI, Keiko; SUGIMOTO, Naoki
2C4-51
Identification of oncogene TLS as a G-quadruplex-binding protein (Grad. Sch. Integr. Sci. Eng., Shizuoka Univ.) º YAGI, Ryota; OYOSHI, Takanori
2C4-52
Synthesis and evaluation of ligand for selective induction of topologies in telomeric G-quadruplex (Grad. Sch. Fac. Eng., Tokyo Univ. of Agri. and Technol.) º MA, Yue; SASAKI, Shogo; NAGASAWA, Kazuo
Saturday, March 18, AM
Chair: NAKATA, Eiji
(09:00-10:00)
* 8:50-9:00: interval for laptop PC connection.(3C4-01, 3C4-02, 3C4-03, 3C4-04, 3C4-05)
3C4-01
Structural analysis of DNA containing A-tracts sequences using orientation-depending FRET (Sch. Eng., Nagoya Univ.) º KOKUBO, Yuuta; KAWAI, Hayato; KASHIDA, Hiromu; ASANUMA, Hiroyuki
3C4-02
Evaluation of multistrand formation by aTNA tethering artificial bases (Grad. Sch. Eng., Nagoya Univ.) º HATTORI, Yuhei; TAZOE, Kaho; INOUE, Tadashi; KASHIDA, Hiromu; ASANUMA, Hiroyuki
3C4-03
Topology control of synthetic polymers using DNA helicity (Fac. Chem. Materials and Bioeng., Kansai Univ.) º YAMASAKI, Yuta; IKEDA, Yuta; AKAMATSU, Naohide; KUZUYA, Akinori; OHYA, Yuichi
3C4-04
Nucleic Acids Chemistry beyond the Watson-Crick Double Helix (35) : Structure and stabilization of DNA under cationic comb-type copolymers as mimicked chromatin condition (FIRST, Konan Univ.) º ZOUZUMI, Yu-ki; YAMAGUCHI, Nonoka; SHIMADA, Naohiko; SUGIMOTO, Naoki; MARUYAMA, Atsushi; MIYOSHI, Daisuke
3C4-05*
Development of DNA logic gates to provide a small molecule output in response to microRNA inputs (Univ. of Pittsburgh) º MORIHIRO, Kunihiko; DEITERS, Alexander
Chair: MIYOSHI, Daisuke
(10:10-11:10)
* 10:00-10:10: interval for laptop PC connection.(3C4-08, 3C4-09, 3C4-10, 3C4-12)
3C4-08
Effect of Torsional Constrained DNA Substrates on Cas9 Cleavage (WPI-iCeMS, Kyoto Univ.; WPI-iCeMS, Kyoto Univ.) RÄZ, Michael; HIDAKA, Kumi; STURLA, Shana; SUGIYAMA, Hiroshi; º ENDO, Masayuki
3C4-09
Construction of DNA nanostructure which induces chemical reaction by conformational change (Dep. Chem., Sch. Sci., Kyoto Univ.) º KAMADA, Yuu; TAKEUCHI, Yosuke; TAKENAKA, Tomohiro; EMURA, Tomoko; SUGIYAMA, Hiroshi; ENDO, Masayuki
3C4-10*
Activity of spatially organized enzyme on DNA scaffold (IAE, Kyoto Univ.) º DINH, Huyen; NAKATA, Eiji; MORII, Takashi
3C4-12*
Orthogonal modular adaptors for assembling multiple enzymes on DNA scaffold (IAE, Kyoto Univ.) º NGUYEN, Thang; NAKATA, Eiji; SAIMURA, Masayuki; MORII, Takashi
Chair: HAMACHI, Itaru
(11:20-12:20)
* 11:10-11:20: interval for laptop PC connection.(3C4-15)
3C4-15 CSJ Award for Creative Works
A Bioorganic Chemistry Approach to Understanding Molecular Recognition in Protein-Nucleic Acid Complexes (IAE, Kyoto Univ.) º MORII, Takashi
[Asian International Symposium -Natural Products Chemistry, Chemical Biology/ Biofunctional Chemistry and Biotechnology-]
Saturday, March 18, PM
(13:00-13:10)
3C4-25
Resent biosynthetic study of natural products. (Tokyo Tech.) º Kudo, Fumitaka
Chair: Kigoshi, Hideo
(13:10-13:30)
3C4-26 Invited Lecture
Reconstitution of biosynthetic machinery of fungal secondary metabolites. (Hokkaido Univ.) º Minami, Atsushi
Chair: Kudo, Fumitaka
(13:30-14:00)
3C4-28 Keynote Lecture
Biosynthesis of fungal indole alkaloids. (Academia Sinica) º Hsiao-Ching, Lin
Chair: Oguri, Hiroki
(14:00-14:20)
3C4-31 Invited Lecture
In vitro biosynthetic system for peptides with diverse modified backbones. (The Univ. of Tokyo) º Goto, Yuki
Chair: Arimoto, Hirokazu
(14:30-14:50)
3C4-34 Invited Lecture
Post-translational prenylation of tryptophan. (The Univ. of Tokyo) º Okada, Masahiro
Chair: Murata, Michio
(14:50-15:20)
3C4-36 Keynote Lecture
Marine-derived bioactive natural products and novel biomaterials. (De La Salle Univ.) º Rafael Atillo, Espiritu
Chair: Yoshino, Tomoko
(15:20-15:40)
3C4-39 Invited Lecture
Nanopore sensing with stable lipid bilayers integrated in microdevices. (Tokyo Univ. of Agri. and Tech.) º Kawano, Ryuji
Chair: Ijiro, Kuniharu
(15:40-16:00)
3C4-41 Invited Lecture
Design of synthetic polymer nanoparticles that function as molecular chaperones. (Kyushu Univ.) º Hoshino, Yu
Chair: Atomi, Haruyuki
(16:10-16:40)
3C4-44 Keynote Lecture
Water dehydration mediated underwater adhesion. (Pohang Univ. of Sci. and Tech.) º Dong Soo, Hwang
Chair: Nagatsugi, Fumi
(16:40-17:00)
3C4-47 Invited Lecture
Hybrid fluorescence-Raman imaging to correlate biochemical information to protein expression. (The Univ. of Tokyo) º Liang-da, Chiu
Chair: Aono, Shigetoshi
(17:00-17:30)
3C4-49 Keynote Lecture
Smart nanoplatforms for bioanalytics and disease theranostics. (National Chiao-Tung University) º Hsin-Yun, Hsu
(17:30-17:40)
3C4-52
Closing remarks. (Univ. of Tsukuba) º Kojima, Takahiko
[Biofunctional Chemistry ; Biotechnology]
Sunday, March 19, AM
Chair: UEKI, Ryosuke
(09:00-10:00)
* 8:50-9:00: interval for laptop PC connection.(4C4-01, 4C4-02, 4C4-03, 4C4-04, 4C4-05)
4C4-01
Improvement of binding ability of thrombin binding aptamer bearing un-natural nucleic acid base (Fac. Eng., Tokyo Univ. of Agri. and Technol.) IKEBUKURO, Kazunori; º KONDA, Kaoru; IKUTA, Yuri; YAMAGISHI, Yasuko; TSUKAKOSHI, Kaori
4C4-02
Detection of soluble amyloid beta oligomer based on nucleic acid amplification by using the oligomer specific aptamer (Fac. Eng., Tokyo Univ. of Agri. and Technol.) TSUKAKOSHI, Kaori; º HOSOI, Chihiro; IKEBUKURO, Kazunori
4C4-03
Improvement of sequence discrimination ability of molecular beacon probe using short chain oligomer (Sch. Sci. Tech., Gunma Univ.) º KAWASAKI, Masakazu; MORIGUCHI, Tomohisa; SHINOZUKA, Kazuo
4C4-04
Development of anti-miRNA oligonucleotide composed of acyclic nucleic acid (Grad. Sch. Eng., Nagoya Univ.) º KAMIMOTO, Hiroshi; DONOSHITA, Yuka; MURAYAMA, Keiji; KAMIYA, Yukiko; ASANUMA, Hiroyuki
4C4-05*
Enhanced strand invasion into double-stranded DNA by PNA-NLS conjugates (Sch. Sci., Nagoya Univ.) º AIBA, Yuichiro; URBINA, Gerardo; WATANABE, Yoshihito
Chair: AIBA, Yuichiro
(10:10-11:10)
* 10:00-10:10: interval for laptop PC connection.(4C4-08, 4C4-09, 4C4-11, 4C4-12, 4C4-13)
4C4-08
Synthesis of random penta-peptide modified Naphthyridines, and evaluation of binding to bulge DNA. (ISIR, Osaka Univ.) º ITO, Hiroshi; AIKAWA, Haruo; NAKATANI, Kazuhiko
4C4-09*
Catalytic activity of an RNP receptor library with structural diversity (IAE, Kyoto Univ.) º TAMURA, Tomoki; NAKANO, Shun; MORII, Takashi
4C4-11
High throughput screening for discovery of novel ribosome-binding molecules (Grad. Sch. Sci., Nagoya Univ.; WPI-ITbM, Nagoya Univ.; PRESTO, JST) º YAMASHITA, Shun; SATO, Ayato; ITAMI, Kenichiro; HAGIHARA, Shinya
4C4-12
Coding technology based on oligonucleotides (1) Effort toward development of DNA-encoded OBOC peptide library. (Grad. Sch. Eng., The Univ. of Tokyo) º RYO, Yoshiba; FURUHATA, Takafumi; RYOSUKE, Ueki; JUMPEI, Morimoto; SHINSUKE, Sando
4C4-13
Coding technology based on oligonucleotides (2) Design of artificial nucleic acids for efficient decoding of DNA tags by quantum sequencer (Grad. Sch. Eng., The Univ. of Tokyo) º FURUHATA, Takafumi; OHSHIRO, Takahito; UEKI, Ryosuke; TANIGUCHI, Masateru; SANDO, Shinsuke
Chair: KAMIYA, Yukiko
(11:20-12:20)
* 11:10-11:20: interval for laptop PC connection.(4C4-15, 4C4-17, 4C4-18, 4C4-19)
4C4-15*
Development of functional molecules targeting circulating microRNA (Hakubi Center, Kyoto Univ.; Dep. Chem., Sch. Sci., Kyoto Univ.) º YAMAYOSHI, Asako; ARIYOSHI, Jumpei; KONISHI, Ryo; KOBORI, Akio; ASHIHARA, Eishi; MURAKAMI, Akira; SUGIYAMA, Hiroshi
4C4-17
Development of cancer cell specific cellular uptake system utilizing MMP-9 cleavage activities (IMRAM, Tohoku Univ.) º MATSUSHIMA, Moeka; SUGAI, Hiroka; NAKASE, Ikuhiko; ISHIBASHI, Satoru; YOKOTA, Takanori; SAKAMOTO, Seiji; ARAKI, Yasuyuki; WADA, Takehiko
4C4-18
3'-DNA modified hemi-gapmer type chimeric PRNA derivatives for the effective and catalytic oligonucleotide therapeutics (IMRAM, Tohoku Univ.; Neuro.,Tokyo Med. and Dental Univ.) º INAGAKI, Masahito; UNABARA, Daisuke; UEMATSU, Ryohei; ARAKI, Yasuyuki; SAKAMOTO, Seiji; ISHIBASHI, Satoru; YOKOTA, Takanori; WADA, Takehiko
4C4-19*
Intracellular Delivery of Peptide Ribonucleic Acid by Oligoarigine Conjugation (IMRAM, Tohoku Univ.) º SUGAI, Hiroka; SAKAMOTO, Seiji; ARAKI, Yasuyuki; WADA, Takehiko
Sunday, March 19, PM
Chair: IHARA, Toshihiro
(13:40-14:40)
* 13:30-13:40: interval for laptop PC connection.(4C4-29, 4C4-30, 4C4-31, 4C4-32, 4C4-33)
4C4-29
Effect of DNA sequence alterations on structures and functions of complexes between heme and G-quadruplex DNAs. (Div. of Chem., Fac. Pure Appl. Sci., Univ. of Tsukuba) KATAHIRA, Yuya; º SHIBATA, Tomokazu; MATSUI, Toru; MORIHASHI, Kenji; WATANABE, Akari; NAKAO, Tomomi; YANAGISAWA, Sachiko; OGURA, Takashi; YAMAMOTO, Yasuhiko
4C4-30
Characterization of peroxidase activities and structures of complexes between some fluorinated hemes and G-quadruplex DNA [d(TTAGGG)]4 (Sch. Sci. Eng., Univ. of Tsukuba) º SHINOMIYA, Ryosuke; KATAHIRA, Yuya; SHIBATA, Tomokazu; OGURA, Takashi; YANAGISAWA, Sachiko; NAKAO, Tomomi; SUZUKI, Akihiro; YAMAMOTO, Yasuhiko
4C4-31
Structural characterization of a complex between heme and unimolecular G-quadruplex DNA (Div. of Chem., Fac. Pure Appl. Sci., Univ. of Tsukuba) OCHI, Kentaro; º YAMAMOTO, Yasuhiko; SHIBATA, Tomokazu; HAGIHARA, Masaki; HEMMI, Hikaru
4C4-32
Nucleic Acids Chemistry beyond the Watson-Crick Double Helix (33) : Photocleavage by anionic zinc phthalocyanine targeting mRNA G-quadruplex (FIRST, Konan Univ.) º MURATA, Kohei; SUGIMOTO, Wataru; TAKAGI, Kazuki; SUGIMOTO, Naoki; KAWAUCHI, Keiko; MIYOSHI, Daisuke
4C4-33*
Target gene detection by the peroxidase activity of the complex between hemin and split quadruplex DNA in the presence of lead ion (Fac. Sci., TUS) AKIBA, Ryo; º TORIGOE, Hidetaka
Chair: YAMADA, Takeshi
(14:50-15:50)
* 14:40-14:50: interval for laptop PC connection.(4C4-36, 4C4-37, 4C4-38, 4C4-39, 4C4-40)
4C4-36
Specific binding between metal ion and mismatched base pair involving 5-hydroxyuracil (Fac. Sci., TUS) º ARAKAWA, Fumihiro; YAGUCHI, Ayami; ONO, Akira; TORIGOE, Hidetaka
4C4-37
Regulation of DNA duplex dissociation by radiolytic one-electron reduction of silver ion in mismatched base pair (Coll. Sci. Eng., Aoyama Gakuin Univ.) º MISU, Sotaro; KURIHARA, Ryohsuke; TAMABE, Kazuhito
4C4-38
Control of PNA Invasion Activity by Metal Complex Conjugation (Grad. Sch. Sci., Nagoya Univ.) º HIBINO, Masaki; AIBA, Yuichiro; WATANABE, Yoshihito
4C4-39
Metal-responsive Triplex-forming Oligonucleotides based on 5-Hydroxyuracil DNA Bases (Grad. Sch. Sci., The Univ. of Tokyo) º NISHIYAMA, Kotaro; TAKEZAWA, Yusuke; SHIONOYA, Mitsuhiko
4C4-40*
Nucleic Acids Chemistry beyond the Watson-Crick Double Helix (36) : Stability of nucleic acid structures in the presence of bulky cationic compounds (FIRST, Konan Univ.) MORIMOTO, Ryuta; NAKAI, Hiroki; AYUSAWA, Toshiya; TANINO, Yuichi; SUGIMOTO, Naoki; º NAKANO, Shu-ichi
Chair: MIYOSHI, Daisuke
(16:00-17:00)
* 15:50-16:00: interval for laptop PC connection.(4C4-43, 4C4-45, 4C4-46, 4C4-47)
4C4-43*
Enzymatic cascade reactions on the DNA scaffold (IAE, Kyoto Univ.) º NAKATA, Eiji; DINH, Huyen; NGUYEN, Thang; SAIMURA, Masayuki; MORII, Takashi
4C4-45
Nanoliposomes scaffolded on DNA origami (IAE, Kyoto Univ.) º KONISHI, Hiroaki; NAKATA, Eiji; NAKANO, Shun; MORII, Takashi
4C4-46
Morphological change of liposomes by alkyl-chain-modified oligonucleotides (Grad. Sch. Arts and Sci., The Univ. of Tokyo) º SHOHDA, Koh-ichiroh; SUYAMA, Akira
4C4-47*
Development of cryogenic fluorescence microscope for precise 3D optical imaging of a single biomolecule. (Sch. Sci., Tokyo Tech.) FURUBAYASHI, Taku; MATSISHITA, Michio; º FUJIYOSHI, Satoru