The 100th Annual Meeting of The Chemical Society of Japan

Date: March 22nd - 25th, 2020

Venue: Noda Campus, Tokyo University of Science, Chiba, Japan

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Room E6

Lecture Hall Bldg. K406


[Biofunctional Chemistry ; Biotechnology]


Sunday, March 22, AM


Nucleic Acids (Chemical Synthesis)

Chair: ABE, Hiroshi (09:00-10:00)

* 8:50-9:00: interval for laptop PC connection.(1E6-01, 1E6-02, 1E6-03, 1E6-04, 1E6-05, 1E6-06)

1E6-01
Novel modified adenine for photo-control of artificial nucleic acid SNA by various wavelength of light (Grad. Sch. Eng., Nagoya Univ.) º YAMANO, Yuuhei; MURAYAMA, Keiji; ASANUMA, Hiroyuki

1E6-02#
Coordination-driven Base-pair Switching of 5-Hydroxyuracil Nucleobases towards Development of Metal-responsive DNA Tweezers (Grad. Sch. Sci., The Univ. of Tokyo) º MORI, Keita; TAKEZAWA, Yusuke; SHIONOYA, Mitsuhiko

1E6-03
Synthesis of positional isomers of 2-amino-1,8-naphthyridine dimer and assay of binding with nucleic acid (ISIR, Osaka Univ.) º KUWAHARA, Satoki; DAS, Bimolendu; NAKATANI, Kazuhiko

1E6-04
Development of new photoswitchable molecular glue with improved photoisomerization properties (ISIR, Osaka Univ.) º KOBAYASHI, Shotaro; DOHNO, Chikara; NAKATANI, Kazuhiko

1E6-05
Stereoselective synthesis of boranophosphate RNA by the oxazaphospholidine approach (Fac. Pharm. Sci., TUS) º OKADA, Kyohei; GOTO, Keisuke; SAITO, Tatsuya; KOGURE, Tomoki; SATO, Kazuki; HARA, Rintaro; WADA, Takeshi

1E6-06
Synthesis and properties of oligonucleotides having 2´-O alkylcarbamoylethyl modification. (Sch. Life Sci. Tech., Tokyo Tech.) º KISHIMURA, Tomohiro; TOMORI, Takahito; MASAKI, Yoshiaki; SEIO, Kohji


Chair: WADA, Takeshi (10:10-11:10)

* 10:00-10:10: interval for laptop PC connection.(1E6-08, 1E6-09, 1E6-10, 1E6-11, 1E6-12, 1E6-13)

1E6-08
Synthesis and characterization of oligonucleotides bearing photoreactive nitrobenzyl group for control of aggregate formation (Coll. Sci. Eng., Aoyama Gakuin Univ.) º KIKUTHI, Takuto; TANABE, Kazuhito; NISHIHARA, Tatsuya

1E6-09
Synthesis and functional evaluation of modified nucleic acid (Sch. Sci., Nagoya Univ.) º NOMURA, Kohei; MURASE, Hirotaka; NAKAMOTO, Kosuke; KIMURA, Yasuaki; ABE, Naoko; ABE, Hiroshi

1E6-10
Synthesis and properties of 13C-labeled naphthyridine derivative (ISIR, Osaka Univ.) º SAKURABAYASHI, Shuhei; YAMADA, Takeshi; KAWAI, Gota; NAKATANI, Kazuhiko

1E6-11
Efficient synthesis of stringent response molecule ppGpp using phosphoramidite reagent (Sch. Life Sci. Tech., Tokyo Tech.) º AKAI, Ko; SUGIYAMA, Daiki; OHNO, Kentaro; TOMORI, Takahito; MASAKI, Yosiaki; SEIO, Kohji

1E6-12
Design and synthesis of novel non-natural nucleosides for development of chemically-modified nucleic acid aptamers (IMRAM, Tohoku Univ.) º ITO, Rina; OKAMURA, Hidenori; NAGATSUGI, Fumi

1E6-13
Orthogonal base pair formation by the nucleoside analogues bearing additional hydrogen-bonding units (IMRAM, Tohoku Univ.) º OKAMURA, Hidenori; TRINH HOANG, Giang; NAGATSUGI, Fumi


Chair: NAGATSUGI, Fumi (11:20-12:20)

* 11:10-11:20: interval for laptop PC connection.(1E6-15, 1E6-16, 1E6-17, 1E6-18, 1E6-19)

1E6-15
Synthesis of novel acyclic artificial nucleic acid based on the structure of L-aTNA (Grad. Sch. Eng., Nagoya Univ.) º MURAYAMA, Keiji; IIZUKA, Youhei; ASANUMA, Hiroyuki

1E6-16
Novel acyclic artificial nucleic acid modified with terminal alkyne on the backbone (Grad. Sch. Eng., Nagoya Univ.) º YOKOYAMA, Junya; MURAYAMA, Keiji; ASANUMA, Hiroyuki

1E6-17
5′-C-Aminoalkyl-nucleoside (1): Synthesis and evaluation of (S)-5′-C-aminopropyl-2′-O-methylribonucleoside (Gifu Univ.) º KAJINO, Ryohei; UENO, Yoshihito

1E6-18
5'-C-Aminoalkylnucleoside (2) : Synthesis and evaluation of (S)-5'-aminopropyl-2'-fluoroarabinonucleoside (Fac. Applied Bio. Sci., Gifu Univ.) º ZHOU, Yujun; KAJINO, Ryohei; UENO, Yoshihito

1E6-19*#
Development of A New Method for Chemical Synthesis of Genomic DNAs (Sch. Life Sci. Tech., Tokyo Tech.; CREST, JST) º SUTO, Hiroki; MIYAKE, Yu; IKEDA, Kousuke; MIYAZAKI, Yu; AKAZAWA, Saaya; OHKUBO, Akihiro


Sunday, March 22, PM

Chair: UENO, Yoshihito (13:30-14:30)

* 13:20-13:30: interval for laptop PC connection.(1E6-28, 1E6-29, 1E6-30, 1E6-31, 1E6-32)

1E6-28
Synthesis of 2´-O,3′-C-Linked [3.2.0]Bicycloarabinofuranosyl-thymine derivative. (Sch. Life Sci. Tech., Tokyo Tech.) º WAKATSUKI, Shunsuke; INOUE, Atsushi; MASAKI, Yoshiaki; SEIO, Kohji

1E6-29
Function of oligodeoxynucleotides bearing nitrophenol group at nucleobase (Coll. Sci. Eng., Aoyama Gakuin Univ.) º YOKOTA, Shohei; TANABE, Kazuhito; KURIHARA, Ryohsuke; NISHIHARA, Tatsuya

1E6-30
Synthesis and Hybridization Properties of Artificial RNAs Made Exclusively of Alkynyl Ribonucleotides (Grad. Sch. Med. Pharm. Sci. Edu., Univ. of Toyama) º KUROSAKI, Fumihiro; CHIBA, Junya; INOUYE, Masahiko


Nucleic Acids (Function, Medical)

1E6-31
Comprehensive identification of RNA-small molecule interaction by NGS analysis of Dicer cleavage products (ISIR, Osaka Univ.) º TAKASHIMA, Yusuke; MURATA, Asako; NAKATANI, Kazuhiko

1E6-32*#
Transferrin-Appended Nanocaplets for siRNA Delivery into Deep Tissues (Grad. Sch. Eng., The Univ. of Tokyo) º KOHATA, Ai; P. K., Hashim; OKURO, Kou; AIDA, Takuzo


Chair: DOHNO, Chikara (14:40-15:40)

* 14:30-14:40: interval for laptop PC connection.(1E6-35, 1E6-37, 1E6-39, 1E6-40)

1E6-35*#
Cu(II)-specific Activation of Synthetic DNAzymes Possessing a Pair of 4-Carboxyimidazole-bearing Nucleotides (Grad. Sch. Sci., The Univ. of Tokyo) º HU, Lingyun; NAKAMA, Takahiro; TAKEZAWA, Yusuke; SHIONOYA, Mitsuhiko

1E6-37*#
Allosteric Regulation of Single-stranded DNAzymes Based on Cu(II)-mediated Artificial Base Pairing (Grad. Sch. Sci., The Univ. of Tokyo) º NAKAMA, Takahiro; TAKEZAWA, Yusuke; SHIONOYA, Mitsuhiko

1E6-39
Combination effect of cytosine methylation and molecular crowding on thermodynamic stability of DNA duplexes (FIRST, Konan Univ.) º TSURUTA, Mitsuki; SUGITANI, Yui; SUGIMOTO, Naoki; MIYOSHI, Daisuke

1E6-40
Promotion of guanine damage by singlet oxygen generated from SYBR Green I in DNA condensation (Grad. Sch. Sci. Eng., The Univ. of Electro-Communications) JO, Kento; SAKURAI, Shunsuke; º TANAKA, Makiko


Chair: IHARA, Toshihiro (15:50-16:50)

* 15:40-15:50: interval for laptop PC connection.(1E6-42, 1E6-44, 1E6-45, 1E6-46, 1E6-47)

1E6-42*#
Hypoxia Activated Anticancer Drugs via Selective Bioreduction of Azo and/or Nitro Functionalities (Grad. Sch. Eng., The Univ. of Tokyo) º MORIHIRO, Kunihiko; ISHINABE, Takuro; OKAMOTO, Akimitsu

1E6-44
Promotion of interduplex electron transfer in ψ-type DNA (Grad. Sch. Sci. Eng., The Univ. of Electro-Communications) º SAKURAI, Shunsuke; ESUMI, Mayu; TANAKA, Makiko

1E6-45
Development of pyrene aggregates using DNA backbone for high-brightness CPL expression (Sch. Eng., Nagoya Univ.) KASHIDA, Hiromu; º ITO, Yuka; NISHIKAWA, Keiji; KAKUTA, Takahiro; OGOSHI, Tomoki; ASANUMA, Hiroyuki

1E6-46
Development of nucleic acids fluorescent barcode with sequentially changing fluorescent colors (Grad. Sch. Eng., Nagoya Univ.) º MAKINO, Koki; KASHIDA, Hiromu; ASANUMA, Hiroyuki

1E6-47
Evaluation of the stability of DNA duplex and triplex incorporating photocaged deoxypseudouridine (Sch. Life Sci. Tech., Tokyo Tech.) º YAMADA, Yuji; TAKESHITA, Leo; MASAKI, Yoshiaki; SEIO, Kohji


Chair: OHKUBO, Akihiro (17:00-18:00)

* 16:50-17:00: interval for laptop PC connection.(1E6-49, 1E6-51, 1E6-53, 1E6-54)

1E6-49*
Development of a Next-Generation Nucleic Acid Medicine using nucleic acid analogs (Fac. Adv. Sci. Tech., Kumamoto Univ.) º KATSUDA, Yousuke; SATO, Shin-ichi; HAGIHARA, Masaki; KAMURA, Takuto; KITAMURA, Yusuke; IHARA, Toshihiro

1E6-51*#
Nucleic Acids Chemistry beyond the Watson-Crick Double Helix (64): Effects of malignant alteration in cancer cells on the DNA structures and transcript mutations (FIBER, Konan Univ.) º TATEISHI-KARIMATA, Hisae; KAWAUCHI, Keiko; OHYAMA, Tatsuya; SUGIMOTO, Naoki

1E6-53
Highly Efficient Translation by Introducing Chemical Modification into mRNA (Grad. Sch. Sci., Nagoya Univ.) º KAWAGUCHI, Daisuke; KODAMA, Ayumi; SHIMIZU, Yoshihiro; ABE, Naoko; NAKAMOTO, Kousuke; HASHIYA, Fumitaka; KIMURA, Yasuaki; ABE, Hiroshi

1E6-54
Acquisition of RNA aptamer to regulate Protein-Protein Interaction (Kumamoto Univ.) º FUCHIGAMI, Yusuke; KATSUDA, Yousuke; INOUE, Maimi; KITAMURA, Yusuke; YAMAGUCHI, Yoshihiro; IHARA, Toshihiro


Chair: MIYOSHI, Daisuke (18:10-19:00)

* 18:00-18:10: interval for laptop PC connection.(1E6-56, 1E6-57, 1E6-58, 1E6-59, 1E6-60)

1E6-56
Effects of polyamines on DNA structural changes and guanine photodamage (The Univ. of Electro-Communications) º ESUMI, Mayu; SAKURAI, Shunsuke; TANAKA, Makiko

1E6-57
Synthesis of N3-position-modified thioflavin T with a tertiary amine and its binding and fluorescence properties for guanine quadruplexes (Grad. Sch. Integrated Basic Sci., Nihon Univ.) º YOSHIMURA, Miki; KATAOKA, Yuka; KUWAHARA, Masayasu

1E6-58
Development of DNA-protein complex aiming high selective recognition of membrane antigens (Grad. Sch. Sci., Eng., Aoyama Gakuin Univ.) º MOTOHASHI, Yuto; MORITANI, Shuhei; NISHIHARA, Tatsuya; TANABE, Kazuhito

1E6-59
Development of new DNA assembly method for the genome synthesis (Grad. Sch. Sci., Nagoya Univ.) º MURASE, Hirotaka; NAKAMOTO, Kosuke; ABE, Naoko; FUKUI, Ryusuke; HASHIYA, Fumitaka; KIMURA, Yasuaki; ABE, Hiroshi

1E6-60
Withdrawn


Monday, March 23, AM


Nucleic Acids (Quadruplexes)

Chair: XU, Yan (09:00-10:00)

* 8:50-9:00: interval for laptop PC connection.(2E6-01, 2E6-02, 2E6-03, 2E6-04, 2E6-05, 2E6-06)

2E6-01
Elucidation of correlation between push and pull effects on peroxidase activity of a complex between heme and an all parallel-stranded tetrameric G-quadruplex DNA (Div. of Chem., Fac. Pure Appl. Sci., Univ. of Tsukuba) º HAGIWARA, Shota; SHINOMIYA, Ryosuke; MOMOTAKE, Atsuya; YAMAMOTO, Yasuhiko; SUZUKI, Akihiro; NEYA, Saburou

2E6-02
Characterization of all parallel-stranded dimeric G-quadruplex DNAs formed from human telomere-related sequences and their complexes with heme (Div. of Chem., Fac. Pure Appl. Sci., Univ. of Tsukuba) º OKAMOTO, China; SHINOMIYA, Ryosuke; YAMADA, Kao; MOMOTAKE, Atsuya; YAMAMOTO, Yasuhiko

2E6-03
Elucidation of Molecular Mechanism Responsible for Enhancement of Peroxidase Activity of a Complex between Heme and a G-quadruplex DNA (Div. of Chem., Fac. Pure Appl. Sci., Univ. of Tsukuba) ARAKI, Haruka; MOMOTAKE, Atsuya; º YAMAMOTO, Yasuhiko; OCHIAI, Takuro; SHIMADA, Naohiko; MARUYAMA, Atsushi

2E6-04
Structure development and fluorescent evaluation of G4 ligands for detection of G-quadruplex (Grad. Sch. Fac. Eng., Tokyo Univ. of Agri. and Technol.) º WAKABAYASHI, Yuki; SAITO, Ryota; TERA, Masayuki; MA, Yue; NAGASAWA, Kazuo

2E6-05
Synthesis of light-up type ligands, which shows specifically fluorescent in the presence of G-quadruplex (Fac. Eng., Tokyo Univ. of Agri. and Technol.) º WATATANI, Naruyuki; WAKABAYASHI, Yuki; MA, Yue; NAGASAWA, Kazuo

2E6-06
Enzymatically synthesis and fluorescence detection of various beads-on-a-string-like G-quadruplexes (Grad. Sch. Integrated Basic Sci., Nihon Univ.) º KATAOKA, Yuka; FUJITA, Hiroto; KUWAHARA, Masayasu


Monday, March 23, PM

Chair: KUWAHARA, Masayasu (12:30-13:30)

* 12:20-12:30: interval for laptop PC connection.(2E6-22, 2E6-23, 2E6-24, 2E6-25, 2E6-26, 2E6-27)

2E6-22
Characterization of an imidazole adduct of a heme-DNA complex (Sch. Sci. Eng., Univ. of Tsukuba) º NAKAJIMA, Yusuke; MOMOTAKE, Atsuya; YAMAMOTO, Yasuhiko

2E6-23
Complexes between G-quadruplex DNA and Phthalocyanine derivatives (Div. of Chem., Fac. Pure Appl. Sci., Univ. of Tsukuba) UCHIYAMA, Mami; SHIBATA, Tomokazu; º MOMOTAKE, Atsuya; IKEUE, Takahisa; MATSUI, Toru; YAMAMOTO, Yasuhiko

2E6-24
Synthesis and evaluation of linear type polyoxazoles as G-quadruplex ligands against telomeric DNA (Grad. Sch. Fac. Eng., Tokyo Univ. of Agri. and Technol.) º SASAKI, Shogo; BAO, Hong-liang; ISHIZUKA, Takumi; XU, Yan; TERA, Masayuki; MA, Yue; NAGASAWA, Kazuo

2E6-25#
DNA Quadruplex-Duplex Hybrids as Bimolecular Scaffolds for Asymmetric Catalysis (Grad. Sch. Sci., Kyoto Univ.; Fac. Sci., Kyoto Univ.) º YUM, Jihye; PARK, Soyoung; SUGIYAMA, Hiroshi

2E6-26
Effects of coexisting cation on DNA G-quadruplex ligand screening (FIRST, Konan Univ.) º HASHIMOTO, Yoshiki; TAKAMIYA, Nagisa; SUGIMOTO, Naoki; AKASHI, Satoko; MIYOSHI, Daisuke

2E6-27#
Nucleic Acids Chemistry beyond the Watson-Crick Double Helix (58): The effect of molecular crowding on the stability of RNA G-quadruplexes with various number of quartets and loops (FIBER, Konan Univ.) º MATSUMOTO, Saki; TATEISHI, Hisae; TAKAHASHI, Shuntaro; SUGIMOTO, Naoki


Nucleic Acids (Structure)

Chair: YAMAMOTO, Yasuhiko (13:40-14:40)

* 13:30-13:40: interval for laptop PC connection.(2E6-29, 2E6-30, 2E6-31, 2E6-32)

2E6-29
Development of Novel G4 Ligand for Fluorescence Detection of G-quadruplex (G4) (Grad. Sch. Sci., Chiba Univ.) º ISHIDA, Shunsuke; ARAI, Takayoshi; IIDA, Keisuke

2E6-30
Nucleic Acids Chemistry beyond the Watson-Crick Double Helix (63): Accumulation mechanism for GGGGCC repeated RNA G-quadruplex with dipeptide repeats using molecular simulations (FIBER, Konan Univ.) º OHYAMA, Tatsuya; TATEISHI, Hisae; TANAKA, Shigenori; SUGIMOTO, Naoki

2E6-31
X-ray crystal structure of a reverse binding orientation cyclic-PIP and DNA complex (Dep. Chem., Sch. Sci., Kyoto Univ.) º ABE, Katsuhiko; HIROSE, Yuki; EKI, Haruhiko; TAKEDA, Kazuki; ENDO, Masayuki; BANDO, Toshikazu; SUGIYAMA, Hiroshi

2E6-32 Young Scholar Lectures of CSJ#
Chemical regulation of gene expression based on the topology of DNA structures (FIBER, Konan Univ.) º TAKAHASHI, Shuntaro


Chair: NAGASAWA, Kazuo (16:50-17:40)

* 16:40-16:50: interval for laptop PC connection.(2E6-48, 2E6-49, 2E6-50, 2E6-51, 2E6-52)

2E6-48
Direct observation of higher-order structure of CUG repeat RNAs assembly (IAE, Kyoto Univ.) º SHIMIZU, Musashi; NAKANO, Shun; TAJIMA, Shunsuke; MORII, Takashi

2E6-49
Encapsulation of enzymes arranged on DNA nanostructures with nanoliposomes (Grad. Sch. Energy Sci., Kyoto Univ.) º WAKISAKA, Tomohiko; KONISHI, Hiroaki; DINH, Huyen; NAKATA, Eiji; MORII, Takashi

2E6-50
High-speed AFM observation of light drive a DNA origami Molecular. (Fac. Chem. Materials and Bioeng., Kansai Univ.) º NISHIKAWA, Tomoki; MORITAKA, Yuto; ISHIKAWA, Shumpei; OHYA, Yuichi; KUZUYA, Akinori

2E6-51
Estimation of Molecular Chain Length of Synthetic Polymers using DNA Origami Molecular Machine (Fac. Chem. Materials and Bioeng., Kansai Univ.) º HASHIMOTO, Yuki; ITO, Ryota; ISHIKAWA, Shumpei; OHYA, Yuichi; KUZUYA, Akinori

2E6-52
Distance Dependency of Electroless Plating between Enzyme and AuNPs on DNA Origami Structure (Fac. Chem. Materials and Bioeng., Kansai Univ.) º ISHIKAWA, Shumpei; ISLAM, Md. Sirajul; AKAMATSU, Naohide; OHYA, Yuichi; KUZUYA, Akinori


Tuesday, March 24, AM


Nucleic Acids (Chemical Synthesis, Molecular Recognition)

Chair: MORIHIRO, Kunihiko (09:00-10:00)

* 8:50-9:00: interval for laptop PC connection.(3E6-01, 3E6-02, 3E6-03, 3E6-04, 3E6-05, 3E6-06)

3E6-01
Increase of melting temperature of duplex DNA does not usually indicate specific binding between metal ion and mismatched base pair (Fac. Sci., TUS) ARAKAWA, Fumihiro; º KIDA, Hayahide; ADACHI, Saki; ONO, Akira; URATA, Hidehito; HIRABAYASHI, Kei; TORIGOE, Hidetaka

3E6-02
Specific binding between metal ion and mismatched base pair under molecular crowding condition (Fac. Sci., TUS) º NAKAYAMA, Sumire; ADACHI, Saki; ONO, Akira; HIRABAYASHI, Kei; TORIGOE, Hidetaka

3E6-03
Development of pseudo complementary SNA for improving RNA recognition ability (Grad. Sch. Eng., Nagoya Univ.) º SATO, Fuminori; MURAYAMA, Keiji; KAMIYA, Yukiko; ASANUMA, Hiroyuki

3E6-04#
Chiral Assembly of Cu(II)-Complexes within Glycol Nucleic Acids (Grad. Sch. Sci., The Univ. of Tokyo) º LEON, Jens Christian; TAKEZAWA, Yusuke; NAKAYA, Manabu; SHIONOYA, Mitsuhiko

3E6-05#
Synthesis and the properties of NA Dimer (ISIR, Osaka Univ.) º CHEN, Qingwen; YAMADA, Takeshi; MURATA, Asako; NAKATANI, Kazuhiko

3E6-06#
Synthesis and nucleic acid binding property of a series of quinoxaline-2,3-dione derivatives (ISIR, Osaka Univ.) º XING, Zilu; SHIBATA, Tomonori; NAKATANI, Kazuhiko


Nucleic Acids (Molecular Recognition, Function)

Chair: TORIGOE, Hidetaka (10:10-11:10)

* 10:00-10:10: interval for laptop PC connection.(3E6-08, 3E6-10, 3E6-12, 3E6-13)

3E6-08*#
Evaluation of oligodeoxynucleotides containing tricyclic 2-oxobenzo[b][1,8]naphthyridine that targets adenine nucleobase (Grad. Sch. Pharm., Osaka Univ.) º KISHIMOTO, Yuki; FUJII, Akane; NOZAKI, Natsumi; NAKAGAWA, Osamu; OBIKA, Satoshi

3E6-10*#
Inhibition of receptor dimerization using a DNA aptamer and its effect on cell signaling (Grad. Sch. Eng., The Univ. of Tokyo) º EGUCHI, Akihiro; KUWATA, Keiko; NAGATOISHI, Satoru; TSUMOTO, Kouhei; UEKI, Ryosuke; SANDO, Shinsuke

3E6-12#
Assembly of ruthenium complexes on dsDNA using mismatch binding ligand (ISIR, Osaka Univ.) º NI, Lu; YAMADA, Takeshi; NAKATANI, Kazuhiko

3E6-13#
Nucleic Acids Chemistry beyond the Watson-Crick Double Helix (59): Prediction method for the stability of RNA/DNA hybrid duplex under a physiological condition (FIBER, Konan Univ.) º BANERJEE, Dipanwita; TATEISHI-KARIMATA, Hisae; OHYAMA, Tatsuya; TRAJKOVSKI, Marko; TOPLISHEK, Maria; TAKAHASHI, Shuntaro; ENDOH, Tamaki; PLAVEC, Janez; SUGIMOTO, Naoki


Nucleic Acids (Sensing)

Chair: ENDOH, Tamaki (11:20-12:20)

* 11:10-11:20: interval for laptop PC connection.(3E6-15, 3E6-16, 3E6-17, 3E6-19, 3E6-20)

3E6-15
Development of NIR fluorescent probe responsive to the phosphatase activity in nuclei (Grad. Sch. Sys. Eng., Wakayama Univ.) º SOEDA, Takayuki; SAKAMOTO, Takashi

3E6-16
Synthesis of a Thioflavin T dimer and its evaluation of fluorescence properties (Grad. Sch. Integrated Basic Sci., Nihon Univ.) º WATAHIKI, Kenta; FUJITA, Hiroto; KATAOKA, Yuka; KUWAHARA, Masayasu

3E6-17*
Development of highly sensitive detection of mRNA (Grad. Sch. Integrated Basic Sci., Nihon Univ.) º FUJITA, Hiroto; KATAOKA, Yuka; WATAHIKI, Kenta; KUWAHARA, Masayasu

3E6-19
Construction and Evaluation of an Orientation-Dependent FRET Pair Using Fluorescent Thymine and Cytosine Analogues (Dep. Chem., Sch. Sci., Kyoto Univ.) º HIRASHIMA, Shingo; PARK, Soyoung; SUGIYAMA, Hiroshi

3E6-20#
Synthesis of fluorescent nucleoside analogues and their application as dual probes for the non-canonical DNA structures (Grad. Sch. Sci., Kyoto Univ.) º WEE, Wen, Ann; YUM, Jihye; HIRASHIMA, Shingo; PARK, Soyoung; SUGIYAMA, Hiroshi


Tuesday, March 24, PM


Nucleic Acids (Structure, Function)

Chair: KATSUDA, Yousuke (13:50-14:50)

* 13:40-13:50: interval for laptop PC connection.(3E6-30, 3E6-32, 3E6-34, 3E6-35)

3E6-30*#
Improvement of fluorescent aptamer focusing on its G-quadurplex and design of pH-sensitive Baby Spinach aptamer (Grad. Sch. Fac. Eng., Tokyo Univ. of Agri. and Technol.; University of Rome Tor Vergata) º UENO, Kinuko; TSUKAKOSHI, Kaori; PORCHETTA, Alessandro; RICCI, Francesco; IKEBUKURO, Kazunori

3E6-32*#
Nucleic Acids Chemistry beyond the Watson-Crick Double Helix (57) : Parameters for prediction of DNA duplex stabilities under the crowding conditions (FIBER, Konan Univ.; FIRST, Konan Univ.) º GHOSH, Saptarshi; TAKAHASHI, Shuntaro; OHYAMA, Tatsuya; ENDOH, Tamaki; TATEISHI-KARIMATA, Hisae; SUGIMOTO, Naoki

3E6-34#
Development of Photo-cleavable Protecting Pro-oligos for Membrane-permeable Delivery (Grad. Sch. Eng., The Univ. of Tokyo) º ZHANG, Qiaoyu; MORIHIRO, Kunihiko; OKAMOTO, Akimitsu

3E6-35
Oligonucleotides that response upon pH change: Functional substituent bearing imine bond and their pH response (Grad. Sch. Sci., Eng., Aoyama Gakuin Univ.) º TOMIMIZU, Shunichiro; NISHIHARA, Tatsuya; KURIHARA, Ryohsuke; TANABE, Kazuhito


Nucleic Acids (Sensing, Function)

Chair: SEIO, Kohji (15:00-16:00)

* 14:50-15:00: interval for laptop PC connection.(3E6-37, 3E6-39, 3E6-40, 3E6-41, 3E6-42)

3E6-37*
Development of electrochemical molecular beacon and its application to the detection of nucleic acids in a homogeneous solution (Fac. Adv. Sci. Tech., Kumamoto Univ.) º KITAMURA, Yusuke; MISHIO, Kotaro; IKEDA, Boui; KATSUDA, Yousuke; IHARA, Toshihiro

3E6-39#
A Biofunctional SNA Molecular Beacon for Detecting T790M Point Mutation (Grad. Sch. Eng., Nagoya Univ.) º LIU, Zehua; MURAYAMA, Keiji; ASANUMA, Hiroyuki

3E6-40#
Intercalation-induced triplex-forming linear probe for dsDNA detection with high sensitivity (Grad. Sch. Eng., Nagoya Univ.) º CHEN, Yanglingzhi; MURAYAMA, Keiji; ASANUMA, Hiroyuki

3E6-41
Withdrawn

3E6-42
Synthesis of malachite green derivative and evaluation of fluorescence properties for nucleotide strands (Grad. Sch. Integrated Basic Sci., Nihon Univ.) º TAMURA, Miyuki; KATAOKA, Yuka; KUWAHARA, Masayasu


Nucleic Acids (Medical, Structure)

Chair: UEKI, Ryosuke (16:10-17:10)

* 16:00-16:10: interval for laptop PC connection.(3E6-44, 3E6-45, 3E6-46, 3E6-47, 3E6-48, 3E6-49)

3E6-44
Development of light harvesting antenna using DNA junction with multiple fluorophores (Grad. Sch. Eng., Nagoya Univ.) º AZUMA, Hidenori; KASHIDA, Hiromu; ARAKI, Yasuyuki; WADA, Takehiko; ASANUMA, Hiroyuki

3E6-45
Crystal structures of acyclic nucleic acid-RNA hybrids (Grad. Sch. Eng., Nagoya Univ.) º KAMIYA, Yukiko; SATOH, Tadashi; KODAMA, Atsuji; SUZUKI, Tatsuya; UCHIYAMA, Susumu; KATO, Koichi; ASANUMA, Hiroyuki

3E6-46
Multiple releasing system of small molecules in response to microRNA (The Univ. of Tokyo) º FUKUI, Daisuke; MORIHIRO, Kunihiko; OKAMOTO, Akimitsu

3E6-47
Ce(IV)/EDTA complex for RNA structure analysis (Fac. Med., Univ. of Miyazaki) º ISHIZUKA, Takumi; XU, Yan

3E6-48#
A trifluoromethylation 2’-deoxy-guanosine derivative for G-quadruplex and Z-DNA structure study (Fac. Med., Univ. of Miyazaki) º BAO, Hongliang; ISHIZUKA, Takumi; XU, Yan

3E6-49
Molecular dynamics simulation of RNA duplex with 2',5'-nucleotide under high pressure (Sch. Life Sci. Tech., Tokyo Tech.) º MIYAZAKI, Sho; MASAKI, Yoshiaki; SEIO, Kohji


Wednesday, March 25, AM


Nucleic Acids (Medical, Structure)

Chair: TAKAHASHI, Shuntaro (09:00-10:00)

* 8:50-9:00: interval for laptop PC connection.(4E6-01, 4E6-02, 4E6-03, 4E6-04, 4E6-05, 4E6-06)

4E6-01#
Fluctuation of DNA methylation in LINE-1 caused by metal ions (Grad. Sch. Eng., The Univ. of Tokyo) º LIU, Shan; TAKEUCHI, Fumika; MORIHIRO, Kunihiko; OKAMOTO, Akimitsu

4E6-02
DNA transition of cytosine derivatives in DNA strand toward for genome editing by using reversible DNA photo-cross-linking (Sch. Mat. Sci., JAIST) º NAKAMURA, Shigetaka; SETHI, Siddhant; WAN, Licheng; FUJIMOTO, Kenzo

4E6-03
G-quadruplex binding protein selective modification with hemin-activated luminol derivatives (Grad. Sch. Integrated Sci. and Tech., Shizuoka Univ.) º MASUZAWA, Tatsuki; SATO, Shinichi; NAKAMURA, Hiroyuki; OYOSHI, Takanori

4E6-04#
Direct observation of nucleosome interaction in DNA frame using high-speed AFM (Dep. Chem., Sch. Sci., Kyoto Univ.) º FENG, Yihong; HIDAKA, Kumi; SUGIYAMA, Hiroshi; ENDO, Masayuki

4E6-05
Liquid-liquid phase separation of short G-quadruplex RNA oligonucleotides and RGG oligo peptides (FIRST, Konan Univ.) º KOHATA, Kazuki; SUGIMOTO, Wataru; KAWAUCHI, Keiko; SUGIMOTO, Naoki; MIYOSHI, Daisuke

4E6-06
Analysis of the structural stability and dynamics of nucleic acids forming non-canonical structures using in-cell NMR (Grad. Sch. Energy Sci., Kyoto Univ.) º SAKAMOTO, Tomoki; YAMAOKI, Yudai; NAGATA, Takashi; KATAHIRA, Masato


Nucleic Acids (Structure)

Chair: ENDO, Masayuki (10:10-11:10)

* 10:00-10:10: interval for laptop PC connection.(4E6-08, 4E6-10, 4E6-11, 4E6-12)

4E6-08*#
Nucleic Acids Chemistry beyond the Watson-Crick Double Helix (60) : Interaction analyses between natural alkaloids and RNAs with different structure motifs (FIBER, Konan Univ.; FIRST, Konan Univ.) º ENDOH, Tamaki; SATPATHI, Sagar; SUGIMOTO, Naoki

4E6-10#
Nucleic Acids Chemistry beyond the Watson-Crick Double Helix (61) : Effect of Neighboring Base Pairs of Cytosine Bulge on Berberine Induced RNA Stabilization (FIBER, Konan Univ.; FIRST, Konan Univ.) º SATPATHI, Sagar; ENDOH, Tamaki; SUGIMOTO, Naoki

4E6-11#
Nucleic Acids Chemistry beyond the Watson-Crick Double Helix (62) : Transformation of selective i-motif DNAs induced by flavonoid (FIBER, Konan Univ.) º TAKAHASHI, Shuntaro; BHOWMIK, Sudipta; SUGIMOTO, Naoki

4E6-12*#
Enzymatic Reactions on Topologically-Interlocked DNA Structures Inside a DNA Origami Frame (IAE, Kyoto Univ.) º RAJENDRAN, Arivazhagan; PARK, Seo-jeong; NAKATA, Eiji; KWON, Youngjoo; OSHEROFF, Neil; MORII, Takashi

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