The 100th Annual Meeting of The Chemical Society of Japan

Date: March 22nd - 25th, 2020

Venue: Noda Campus, Tokyo University of Science, Chiba, Japan

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Room D1

Lecture Hall Bldg. K306


[Chemical Biology]


Sunday, March 22, AM

Chair: PRADIPTA, Ambara Rachmat (10:10-11:10)

* 10:00-10:10: interval for laptop PC connection.(1D1-08, 1D1-09, 1D1-10, 1D1-11, 1D1-12, 1D1-13)

1D1-08
Development of coelenterazine analogues exhibiting long-wavelength emission (Grad. Sch. Sci. Eng., The Univ. of Electro-Communications) º TAMAKI, Shota; KIYAMA, Masahiro; KITADA, Nobuo; MORIMITSU, Rei; KIM, Sung-bae; HIRANO, Takashi; MAKI, Shojiro

1D1-09
Photo-Activatable Alkyne Tag for analyzing intercellular molecular dynamics of cell (The Univ. of Tokyo) º NAKAMURA, Sho; YAMAGUCHI, Satoshi; KOSAKA, Takahiro; OKAMOTO, Akimitsu

1D1-10
Development of Photoacoustic Agents Based on Enzyme-Responsive Naphthalocyanine for Tumor Detection (Grad. Sch. Eng., Kyoto Univ.) º IMAIZUMI, Naoto; OE, Masahiro; NOGITA, Kohei; MIKI, Koji; OHE, Kouichi

1D1-11#
Development of DNA nanostructure-based fluorescent sensors (Grad. Sch. Energy Sci., Kyoto Univ.) º GERELBAATAR, Khongorzul; NAKATA, Eiji; ZHANG, Zhengxiao; HIROSE, Hisaaki; FUTAKI, Shiroh; MORII, Takashi

1D1-12
Intracellular oxygen concentration imaging by Pt-porphyrin modified mesoporous silica nanoparticles (Sch. Life Sci. Tech., Tokyo Tech.) º YAMAUCHI, Arisa; ODAI, Shunsuke; ITO, Hidehiro; OKAMOTO, Masaki; KAMACHI, Toshiaki

1D1-13
The synthesis of fluorescent molecules with azide group and its biological behavior in living cells (Grad. Sch. Sci., Eng., Aoyama Gakuin Univ.) º KANDA, Miei; NISHIHARA, Tatsuya; TANABE, Kazuhito


Chair: USUKI, Toyonobu (11:20-12:20)

* 11:10-11:20: interval for laptop PC connection.(1D1-15, 1D1-16, 1D1-17, 1D1-18, 1D1-19, 1D1-20)

1D1-15
Search for cytotoxic marine natural products against PANC-1 human pancreatic cancer cells (Sch. Advanced Sci. Eng., Waseda Univ.) º YONETA, Haruhiko; TANAKA, Kentaro; KURIMURA, Kaho; NAKAO, Yoichi

1D1-16
Search for the bioactive substances from Elettaria cardamomum (Sch. Advanced Sci. Eng., Waseda Univ.) º NISHIOKA, Takayuki; NAKAO, Yoichi

1D1-17
Synthesis and Biological Functions of bacterial cardiolipins (Fac. Sci. Tech., Keio Univ.) º SUZUKI, Keisuke; OHTA, Ippei; ISHIBASHI, Shunichi; TAKAMATSU, Masayuki; FUKASE, Koichi; MATSUMARU, Takanori; INUKI, Shinsuke; FUJIMOTO, Yukari

1D1-18
Synthesis and Biological Functions of Cardiolipins Containing Oxidized Fatty Acids (Fac. Sci. Tech., Keio Univ.) º NABIKA, Etsuko; OHTA, Ippei; SUZUKI, Keisuke; INUKI, Shinsuke; MATSUMARU, Takanori; FUJIMOTO, Yukari

1D1-19
Biological activity of jasmonoyl isoleucine lactone and the affinity with COI1-JAZ co-receptors (Grad. Sch. Life Sci., Tohoku Univ.) º SAITO, Rina; YAMAGAMI, Sohei; OURA, Saki; ABE, Hiroshi; KAJI, Takuya; TAKAOKA, Yousuke; UEDA, Minoru

1D1-20
Development of cancer chemotherapy utilizing 6-aza-artemisinins (Grad. Sch. Fac. Eng., Tokyo Univ. of Agri. and Technol.; Cancer Chemotherapy Ctr., JFCR) º TAKAHASHI, Norihito; MURAMATSU, Yukiko; SEIMIYA, Hiroyuki; OGURI, Hiroki


Sunday, March 22, PM

Chair: KIYONAKA, Shigeki (13:30-14:30)

* 13:20-13:30: interval for laptop PC connection.(1D1-28, 1D1-29, 1D1-30, 1D1-31, 1D1-32)

1D1-28#
Quantitative Mapping of Cellular Labile Zn2+ via Development of Hybrid Fluorescent Probes (IMRAM, Tohoku Univ.) º LIU, Rong; KOWADA, Toshiyuki; WATANABE, Tomomi; MATSUI, Toshitaka; MIZUKAMI, Shin

1D1-29
Development of photoswitchable ligands for protein labeling system (IMRAM, Tohoku Univ.) º MASHITA, Takato; KOWADA, Toshiyuki; SARKAR, Himadri Sekhar; TAKAHASHI, Hiroto; MATSUI, Toshitaka; MIZUKAMI, Shin

1D1-30#
A photoactivatable proximity labeling method for characterizing the DNA-proximal proteome (Grad. Sch. Eng., Kyoto Univ.) º TAKATO, Mikiko; SHIONO, Keiya; TAMURA, Tomonori; HAMACHI, Itaru

1D1-31#
Lysine-targeting covalent modification of His-tag fused membrane proteins in live cells (Grad. Sch. Eng., Kyoto Univ.) º THIMARADKA, Vikram; TAMURA, Tomonori; HAMACHI, Itaru

1D1-32*
Development of fluorogenic substrates selective for GSTP1 and its applications (Grad. Sch. of Life Sci., TUPLS) º MASAYA, Mori; FUJIKAWA, Yuuta; HIDESHI, Inoue


Chair: NIWA, Takashi (14:50-15:40)

* 14:40-14:50: interval for laptop PC connection.(1D1-36, 1D1-37, 1D1-39, 1D1-40)

1D1-36
Generation of reactive species by ruthenium catalysis and application to protein modification (RIKEN CPR; RIKEN BZP; Sch. Mater. & Chem. Tech., Tokyo Tech.; A. Butlerov Inst. of Chem., KFU) º MUGURUMA, Kyohei; TANAKA, Katsunori

1D1-37*#
Reactivity of acrolein released from cancer cells: Application for selective cancer therapy (Biofunc. Syn. Chem. Lab., RIKEN) º PRADIPTA, Ambara Rachmat; AHMADI, Peni; FUJII, Motoko; TANAKA, Katsunori

1D1-39
Development of quantitative acrolein detection method by serine derivative luminescent probe (Grad. Sch. Sci., Osaka Univ.) º NABETANI, Hinako; TSUCHIDA, Hiroya; SHIMOYAMA, Atsushi; FUKASE, Koichi

1D1-40
Cell-selective therapeutic strategy utilizing enzyme-glycocluster complex (RIKEN CPR; RIKEN BZP; RIKEN BDR; Sch. Mater. & Chem. Tech., Tokyo Tech.; A. Butlerov Inst. of Chem., KFU) º NOMURA, Shogo; TAKAHASHI, Mihoko; SAKAMOTO, Kensaku; TANAKA, Katsunori


Monday, March 23, AM

Chair: KOWADA, Toshiyuki (10:10-11:10)

* 10:00-10:10: interval for laptop PC connection.(2D1-08, 2D1-09, 2D1-10, 2D1-11, 2D1-12)

2D1-08
Development of ratiometric fluorescent probes capable of measuring lysosomal pH (Grad. Sch. Pharm., The Univ. of Tokyo) º MIZOGUCHI, Mai; HANAOKA, Kenjiro; KAGAMI, Yu; URANO, Yasuteru

2D1-09#
Development of Acid- and β-Galactosidase-Responsive Photoluminescent Probe for Visualizing Specific Cancer Cells (Grad. Sch. Eng., Kyoto Univ.) º HUO, Wenting; MIKI, Koji; TOKUNAGA, Disuke; MU, Huiying; OE, Masahiro; OHE, Kouichi

2D1-10#
Development of GSH-activatable Fluorogenic Probe Based on BODIPY Scaffold (Grad. Sch. Eng., Kyoto Univ.) º MU, Huiying; MIKI, Koji; OHE, Kouichi

2D1-11
A practical synthesis of 211At-labeled antibody for α-emission cancer therapy (Bio. Syn. Chem. Lab., RIKEN CPR; GlycoTargeting Res. Lab., RIKEN BZP) º FUJIKI, Katsumasa; TANAKA, Katsunori

2D1-12*#
Quantification of neuronal AMPA-type glutamate receptor dynamics by combining ligand-directed chemistry and IEDDA click reaction (Grad. Sch. Eng., Kyoto Univ.; ERATO, JST) º OJIMA, Kento; SHIRAIWA, Kazuki; HAMACHI, Itaru; KIYONAKA, Shigeki


Chair: SHIMOYAMA, Atsushi (11:20-12:20)

* 11:10-11:20: interval for laptop PC connection.(2D1-15, 2D1-17, 2D1-19, 2D1-20)

2D1-15*#
Facile substitution reaction of guaiazulene-3-methanol derivatives with thiols and its application to labelling of thiol-containing biomolecules (IIS, The Univ. of Tokyo) º JIN, Yu; AKAGAWA, Kengo; KUDO, Kazuaki

2D1-17*#
Design and synthesis of derivatives of Spliceostatin A and their biological evaluation toward prostate cancer treatment (Sch. Pharm., Osaka Univ.) º YOSHIKAWA, Yusuke; ISHIBASHI, Airi; NIMURA, Keisuke; MURAI, Kenichi; KANEDA, Yasufumi; ARISAWA, Mitsuhiro

2D1-19
Development of a Ratiometric Fluorescent Zinc Ion Probe Based on Quinoline Chromophore (Fac. Sci. Eng., Doshisha Univ.) º OHASHI, Mami; UEDA, Junpei; NOMURA, Akiko; KODERA, Masahito; HITOMI, Yutaka

2D1-20
Development of New Fluorescent Probes for the Detection of Reactive Oxygen Species (Fac. Sci. Eng., Doshisha Univ.) º FUKUI, Yusuke; UEDA, Junpei; KODERA, Masahito; HITOMI, Yutaka


Monday, March 23, PM

Chair: TAKAOKA, Yosuke (13:30-14:30)

* 13:20-13:30: interval for laptop PC connection.(2D1-28, 2D1-30, 2D1-32, 2D1-33)

2D1-28*#
Cyclic anthraquinones as tetraplex DNA binder for cancer therapeutic application (Grad. Sch. Eng., KIT) º ZOU, Tingting; FUKUDA, Hikaru; WAKAHARA, Daiki; SATO, Shinobu; TAKEUCHI, Hiroshi; TAKENAKA, Shigeori

2D1-30*#
Photoresponsive Cell Membrane Modifiers for Intracellular Drug Delivery (Grad. Sch. Eng., The Univ. of Tokyo) º OTAKE, Saya; OKURO, Kou; AIDA, Takuzo

2D1-32
Indolizine-based photocaging system (RIKEN BDR; IBB, Tokyo Med. and Dental Univ.) º WATANABE, Kenji; TERAO, Nodoka; NIWA, Takashi; HOSOYA, Takamitsu

2D1-33
Development of Isoform-selective Inhibitor against Serine Hydroxymethyltransferase (Fac. Eng., The Univ. of Tokyo) º SHIRAKAWA, Masumi; OTA, Tomoki; SAITO, Yutaro; NONAKA, Hiroshi; SANDO, Shinsuke


Chair: MINOSHIMA, Masahumi (14:40-15:40)

* 14:30-14:40: interval for laptop PC connection.(2D1-35, 2D1-36, 2D1-37, 2D1-38, 2D1-39, 2D1-40)

2D1-35
Hyperpolarization of biomolecules by dynamic nuclear polarization using photo-excited triplet electrons (Grad. Sch. Eng., Kyushu Univ.; CMS, Kyushu Univ.; PRESTO, JST; RIKEN Nishina Center for Accelerator-Based Science) º HAMACHI, Tomoyuki; KOUNO, Hironori; TATEISHI, Kenichiro; UESAKA, Tomohiro; KIMIZUKA, Nobuo; YANAI, Nobuhiro

2D1-36
Enhancing nuclear spin polarization of water based on triplet-DNP (Grad. Sch. Eng., Kyushu Univ.; CMS, Kyushu Univ.; PRESTO, JST; RIKEN Nishina Center for Accelerator-Based Science) º KAWASHIMA, Yusuke; NISHIMURA, Kouki; KOUNO, Hironori; TATEISHI, Kenichiro; UESAKA, Tomohiro; KIMIZUKA, Nobuo; YANAI, Nobuhiro

2D1-37
Phosphorylserine-Polymer Probe for Chemical Exchange Saturation Transfer(CEST)MRI:Effect of a Phosphoryl Group on the CEST Signal of the Probe (Grad. Sch. Eng., Kyoto Univ.) º MURAKAMI, Tomohiro; YAMADA, Hisatsugu; IMAI, Hirohiko; AOYAMA, Yasuhiro; KIMURA, Yu; KONDO, Teruyuki

2D1-38
Synthesis of sulfonyl fluoride based on solid-phase extraction and application of radiofluorination (Sch. Mater. & Chem. Tech., Tokyo Tech.) º TATSUTA, Maho; IZAWA, Akihiro; TANAKA, Hiroshi

2D1-39
Elucidation of side-products during 18F-Fluorination by nucleophilic substitution (Sch. Mater. & Chem. Tech., Tokyo Tech.) º SONG, Ruichong; TAGO, Tetsurou; TOYOHARA, Jyun; TANAKA, Hiroshi

2D1-40
Isotope-dilution LC-MS/MS analysis of desmosines in plasma (Sci. Tec., Sophia Univ.) º MIKAGI, Ayame; IMURA, Akiho; TANIGAWA, Takahiro; ANZAWA, Riki; INOUE, Tomoo; NIIZUMA, Kuniyasu; TOMINAGA, Teiji; USUKI, Toyonobu


Chair: NONAKA, Hiroshi (15:50-16:20)

* 15:40-15:50: interval for laptop PC connection.(2D1-42, 2D1-43, 2D1-44)

2D1-42
Binding Mode Analysis of Ligands with Ligand-dissociation-type Pyrene Probes (Grad. Sch. Bioagr. Sci., Nagoya Univ.; Grad. Sch. Pure Appl. Sci., Univ. of Tsukuba) º ARAI, Atsushi; OBATA, Kohei; HATTORI, Atsunori; WATANABE, Rei; HU, Yaping; IIO, Keita; YONEDA, Kozo; KIGOSHI, Hideo; KITA, Masaki

2D1-43
Exploration of protein reactive groups for gold-nanoparticle based affinity labeling of carbohydrate binding proteins (Grad. Sch. Fac. Eng., Tokyo Univ. of Agri. and Technol.) º SUTO, Nanako; SAKURAI, Kaori

2D1-44
Ligand-clickable gold nanoparticle probes for photoaffinity probes (Grad. Sch. Fac. Eng., Tokyo Univ. of Agri. and Technol.) SAKURAI, Kaori; º MORI, Kanna


Tuesday, March 24, PM

Chair: MURATA, Mihcio (13:30-14:30)

* 13:20-13:30: interval for laptop PC connection.(3D1-28)

3D1-28 CSJ Award for Creative Works#
Biofunctional Study and Therapeutic Application By Chemical Modification of Biomolecules (Sch. Mater. & Chem. Tech., Tokyo Tech.; RIKEN CPR) º TANAKA, Katsunori


Chair: MATSUMARU, Takanori (14:40-15:40)

* 14:30-14:40: interval for laptop PC connection.(3D1-35, 3D1-36, 3D1-37, 3D1-38, 3D1-39, 3D1-40)

3D1-35
Galectin-regulated dynamics and the anti-tumor activity of glycosylated antibody (Grad. Sch. Sci., Osaka Univ.) º YAMAMOTO, Ryuku; KABAYAMA, Kazuya; HATANO, Kanae; MANABE, Yoshiyuki; FUKASE, Koichi

3D1-36
Functional analysis of the glycan on the cell membrane using synthetic glycan display system (Grad. Sch. Sci., Osaka Univ.) º MIURA, Ayane; MIYAKE, Syuto; KABAYAMA, Kazuya; MANABE, Yoshiyuki; SYOMURA, Hiroki; SHIRAKAWA, Asuka; YAMAJI, Toshiyuki; SUZUKI, Kenichi; FUKASE, Koichi

3D1-37
Reactive antagonist approach for the subtype-specific regulation of plant hormone co-receptor COI1-JAZ (Grad. Sch. Sci., Tohoku Univ.) º KOZAKI, Wataru; NUKAZUKA, Yuki; TAKAOKA, Yousuke; UEDA, Minoru

3D1-38
Development of a tool molecule for elucidating the pathological mechanism of host-selective toxin (Grad. Sch. Sci., Tohoku Univ.) º KATO, Nobuki; KURATA, Yoshinori; ISHIMARU, Yasuhiro; UEDA, Minoru

3D1-39
Stereoselective synthesis of vitamin D lactone and identification of its target protein (Grad. Sch. Fac. Eng., Tokyo Univ. of Agri. and Technol.) º SAKAMOTO, Ryota; NAGATA, Akiko; Sedghi Masoud, Shadi; TAKEMOTO, Yasusi; KITTAKA, Atusi; UESUGI, Motonari; ODAGI, Minami; NAGASAWA, Kazuo

3D1-40
Elucidation study of apoptosis-inducing mechanism of jahanyne family, lipopeptides isolated from marine cyanobacteria. (Grad. Sch. Sci. Tech., Keio Univ.) º HOSHINA, Shizuka; IWASAKI, Arihiro; KUDO, Takafumi; TASHIRO, Etu; TERUYA, Toshiaki; IMOTO, Masaya; SUENAGA, Kiyotake


Chair: SUENAGA, Kiyotake (15:50-16:50)

* 15:40-15:50: interval for laptop PC connection.(3D1-42, 3D1-43, 3D1-44, 3D1-45, 3D1-46, 3D1-47)

3D1-42
Discovery of Small Molecules Targeting Flowering-related Protein Complexes (RIKEN CSRS; WPI-ITbM, Nagoya Univ.) º NISHIYAMA, Kotaro; SATO, Ayato; HAGIHARA, Shinya

3D1-43
Screening for the bio-origin of okadaic acid by flow-cytometry (Kanagawa Univ.) º ABE, Takahiro; NAITOU, Takayuki; UEMURA, Daisuke

3D1-44#
Search for Marine Natural Products Facilitating Astrocyte Differentiation (Grad. Sch. Advanced Sci. Eng., Waseda Univ.) º TSE, Wai Lam; OTSUKA, Satoshi; NAKAO, Yoichi

3D1-45
Elucidation of the mechanism of anti-inflammation and adipogenesis inhibition functions of stylissatin A (Grad. Sch. Bioagr. Sci., Nagoya Univ.; School of Integrative and Global Majors, Univ. of Tsukuba; IRC3, AIST) º ZHANG, Menghua; SUNABA, Taiki; SUN, Yiting; SHIBATA, Takahiro; SASAKI, Kazunori; ISODA, Hiroko; KIGOSHI, Hideo; KITA, Masaki

3D1-46
Functional analysis of endogenous ligands that synergistically regulate innate immune function of lipid A. (Grad. Sch. Sci., Osaka Univ.) º ICHINOO, Takushi; SHIMOYAMA, Atsushi; CALDENTEY, Joan; MIZOTE, Keisuke; FUKASE, Koichi

3D1-47
Development of lipid A modification method for the construction of self-adjuvanting vaccine (Grad. Sch. Sci., Osaka Univ.) º YAMANAKA, Yusuke; SHIMOYAMA, Atsushi; FUKASE, Koichi


Chair: KAJI, Takuya (17:00-17:20)

* 16:50-17:00: interval for laptop PC connection.(3D1-49, 3D1-50)

3D1-49#
Synthetic Study of Antibody-Recruiting Molecule toward Influenza for Novel Immunotherapy (Grad. Sch. Sci., Osaka Univ.) º FARABI, Kindi; SIANTURI, Julinton; MANABE, Yoshiyuki; FUKASE, Koichi

3D1-50
Synthesis and Immunological Evaluation of Self-assembling CH401 Peptide as Novel Self-adjuvanting Breast Cancer Vaccine Candidate (Grad. Sch. Sci., Osaka Univ.) º AIGA, Taku; MANABE, Yoshiyuki; ITO, Keita; KABAYAMA, Kazuya; OHSHIMA, Shino; KAMETANI, Yoshie; FURUKAWA, Hiroto; INABA, Hiroshi; MATSUURA, Kazunori; FUKASE, Koichi

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