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Vol. 86, No. 6, June 2013 |
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Web Release Date: March 23, 2013 |
690-697
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Sequential Peptide Ligation by Combining the Cys–Pro Ester (CPE) and Thioester Methods and Its Application to the Synthesis of Histone H3 Containing a Trimethyl Lysine Residue
Toru Kawakami,* Yuichi Akai, Hisao Fujimoto, Chieko Kita, Yuko Aoki, Takehiko Konishi, Masazumi Waseda, Lisa Takemura, and Saburo Aimoto* [Full Text PDF(J-STAGE)] [Full Text HTML]
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A novel sequential ligation strategy, in which native chemical ligation followed by the thioester method was performed, based on the use of the CPE peptide, was applied to the synthesis of histone H3 containing a trimethyl Lys9 residue.
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